An overall challenge in Sub-Saharan Africa is that, governments are inadequately aware about the extent of the vitamin A problem and the potential of vitamin A rich orange-fleshed sweetpotato (OFSP) to contribute to its solutions. Additionally, organizations that do want to work on sweetpotato often lack adequate technical knowledge. This brief outlines the Reaching Agents of Change (RAC) project as it offers unique effort to strengthen advocacy and technical capacity for successful nutrition interventions using OFSP. Through its advocacy efforts since 2011, RAC has generated new investments for promoting orange-fleshed sweetpotato (OFSP) worth 11.4 million USD. RAC has also built institutional capacity to design and implement gender-sensitive projects to ensure wide access and utilization of vitamin A rich OFSP in five selected African countries (Mozambique, Tanzania, Nigeria, Ghana, and Burkina Faso).