Sweetpotato vegetative cuttings Abees cultivar were collected and serologically tested using ELISA and Western blot analysis techniques. Thermotherapy followed by Meristem tip culture technique was used for virus elimination. The virus-free plants obtained by this methods, were subjected to micropropagation regime. Adaptation and acclimatization of in vitro sweetpotato plantlets were carried out in an insect proof greenhouse facility. After adaptation the clean material were used as a source of cuttings to assist Agro-food Co. for enhancing the final production through their bio-farming system.