Sweetpotato is grown for food and feed and is increasingly becoming an important cash crop for many farmers in sub Saharan Africa. Sweetpotato virus disease (SPVD) is, however, one of the major bottlenecks in the expanded use of sweetpotato because it is devastating and can cause 50 to 90% yield loss in susceptible cultivars. Available methods do not adequately control SPVD. There is a need for farmers to have cultivars with desirable traits and durable resistance to SPVD. Development of SPVD resistance is under way in Uganda, led by CIP.