Successful second round of accelerated breeding completed, with the release of 4 orange-fleshed (OFSP) and 3 purple-fleshed (PFSP) drought tolerant sweetpotato varieties in 2016. Third round will be completed in 2019. Early season and terminal drought have negative effects on storage root yield (Fig. 1). Thick vines offer a morphological adaption to drought which may offer an advantage for remobilization of assimilates from leaves and stems to storage roots. Many widely adopted varieties are early bulking and satisfy piece meal harvesting, a desired trait given the predicted shortened seasons in Southern Africa under climate change. Among the 15 drought-tolerant OFSP released in 2011, Delvia and Irene have emerged as the most widely-adapted across different agro-ecologies. First enhanced iron (Fe) OFSP clone (MUSG150522) selected from Umbeluzi populations. Fe bioavailability study from comparing enhanced Fe OFSP clone to low Fe clone conducted among Malawian women of reproductive age by ETH-Zurich in 2019.