Production of high quality early generation sweetpotato seed is expensive. The process requires micro-propagation of pathogen tested tissue culture plantlets, which are then acclimatized and hardened for normal plant growth under screen house conditions. National Agricultural Research Institutes and private sector partners in 11 countries are exploring innovations to reduce cost and increase multiplication rates of early generation seed. Astute monitoring of the seed production environment can lead to incremental changes to the range of factors which influence costs and growth conditions. This flyer presents some of the innovations that have been developed in 2015-2016.