This paper analyzes recent trends in sweetpotato production and use from a global, regional, and sub-regional perspective. Developments in Asia, China in particular and Sub-Saharan Africa merit particular attention as upward trends in output are linked to the changing role of sweetpotato in local food systems. The results presented serve as the basis for recommendation for policymakers and research scientists and are aimed at building on the local momentum to fully exploit sweetpotato’s untapped potential in the new millenium.