Research on meristeming, improved growth media, use of known antivirals, and validation of small RNA sequencing and assembly (sRSA) for virus indexing will be performed at CIP-Lima and IITA-Ibadan for sweetpotato and yam & cassava respectively. Helsinki University will improve the bio-informatics analysis tools and screen potential inhibitors able to control Sweetpotato Virus Disease (SPVD).University of Wisconsin will screen libraries of potential antiviral compounds as new plant therapeutic agents and develop the quickchip for field based diagnostics. Training will be performed in several other African countries.